Antineoplastic Terbinafine HCl Powder CAS 78628-80-5 Terbinafine

• Customization: Available
• CAS No.: 78628-80-5
• Formula: /
• Model NO.: Terbinafine
• Classification: High Purity Material
• Grade: Pharmaceuticals Grade
• Specific Usage: For Biological Purpose, For Tissue Medium Purpose, Pratical Use
• Content: Standard
• Usage: Laboratory Reagents, Analytical Reagents
• Source: Dry Powder
• Habit Appellation: Chemical Medicine
• Application: Scientific Research, Health, Agriculture
• Property: Vitamin
• Product Name: Terbinafine Hydrochloride
• Appearance: White Powder
• Spec: 98%
• Active Ingredients: Dutasteride
• Test Method: HPLC UV
• Cultivation Method: Terbinafine
• Maximum Order Quantity: 1 Kilogram
• Tasted: Characteristic
• Original: China
• Certificate: ISO,CE Kosher
• CAS: 78628-80-5
• Type: API
• Transport Package: 1kg/Bag 25kgs/Drum
• Specification: 98%
• Trademark: Hench
• Origin: China
• Production Capacity: 10000kg/Year

Product Description

Antineoplastic Terbinafine HCl Powder CAS 78628-80-5 Terbinafine

 

Product Name: Terbinafine HCL

Purity: 99%min

Appearance: White crystalline powder

CAS No.: 78628-80-5

EINECS: 245-385-8

Molecular formula: C21H25N·HCl

Molecular weight: 327.9

Terbinafine hydrochloride a synthetic allyla antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.  

Terbinafine·HCl a member of the allyl class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.  

Terbinafine hydrochloride has a fungicidal effect on skin fungi and an inhibitory effect on Candida albicans. It is suitable for skin and nail infections caused by superficial fungi, such as ringworm, ringworm of the body, ringworm of the femur, ringworm of the feet, ringworm of the nail and Candida albicans infection of the skin caused by Trichophyton rubrum, Microsporum canis and Flocculus epidermidis.

 

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methan and dichlorome, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.

1. Terbinafine Hcl is mainly effective on the dermatophyte group of fungi.
2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.
3. Oral 250mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 
4. Terbinafine may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.

 

Item	Specification	Result		Method
Description
Appearance	White powder	Complies		Visual
Odor	Characteristic	Complies		Organoleptic
Taste	Characteristic	Complies		Organoleptic
Part Used	Leaf	Complies
Particle Size	100% through 80 mesh	Complies		CP2015
Bulk Density	0.20g/ml~0.40g/ml	0.25g/ml		CP2015
Maker Compounds
Chemical Test
Loss on drying	≤5.00%	3.8%			GB 5009.3
Heavy Metals
Total Heavy Metals	≤10ppm	Conforms		GB 5009.74
Arseni	≤0.5ppm	Conforms		GB 5009.11
Lead	≤0.5ppm	Conforms		GB 5009.12
Mercur	≤0.1ppm	Conforms		GB 5009.3
Microbiological Tests
TotalPlate Count	≤1000cfu/g	110cfu/g		CP2015
Yeast&Mold	≤100cfu/g	20cfu/g		CP2015
Staphylococcus	Negative	Negative		CP2015
Salmonella	Negative	Negative		CP2015
E. Coli	Negative	Negative		CP2015
storage	Store in cool and dry place,keep away from strong light heat.
Genetic Modification State	The product is GMO free products.
Free Radiation effect	The product is not been irradiated.
Conclusion:	Conform
Tested by:	Mr. Yang Fangchao	Approved by:	Mr. Niu Jicheng

1. Can I buy a sample for evaluation?
Yes. There are no uniform standards for different products. Please consult the salesman for details


2. How do I pay?
We accept wire transfer and western union.


3. How much is the freight?
Transport costs vary according to the mode of transport and the country. Shipping costs to western European countries are generally slightly higher than to the United States. Freight to Asia is slightly lower than to the United States.


4. Does the freight include local taxes, import duties and other import-related charges?
The freight does not include any tax. Local taxes, import duties, customs clearance, or any other import-related charges are levied by your government and the buyer is responsible for these import-related charges. Please check with your local customs for more information.


5. What transportation options do I have?
As we strive to provide value and flexibility to our customers, we offer different options to deliver your order.
1g-100kg, (EMS/UPS/FedEx)
Over 100kg, air or sea


6. How long is the lead time?
Small orders will be shipped in 3 days and large orders in 7-10 days.